By Mike Allen (@mikeallen; mallen@politico.com) and Daniel Lippman (@dlippman; dlippman@politico.com)DRIVING THE CONVERSATION: Rubio pile-on at tonight’s debate – “Rubio walks into the lions’ den: ‘There is no question that the target on our back has increased,’ says Rubio adviser,” by Shane Goldmacher in Manchester: “Trump may be back on the debate stage but Rubio’s the candidate everyone’s looking to take down.