The Chicago White Sox had an opportunity to inch closer to first place ahead of a big series against the division-leading Guardians in Cleveland. Instead, they closed out a homestand with a clunker Thursday against the Houston Astros. The Sox surrendered four home runs, including two two-run homers to Alex Bregman, in a lopsided 21-5 loss in front of 24,407 at Guaranteed Rate Field. A series that began with a pair of thrilling wins for the Sox ended with a thud.