How did a homeless drug addict in New York land the lead role in Heaven Knows What, a highly praised new drama? Two years ago, Arielle Holmes was working as a dominatrix named Siouxsie at a club called Pandora’s Box. After she finished her shift she’d sleep in a doorway or park bench, then, when morning dawned, supplement her income by panhandling on New York’s Upper West Side..One day, she was stopped by a man as she went into the subway.