Panik hit a go-ahead sacrifice fly in the seventh inning, Nunez had a two-run double in his first start with San Francisco and the Giants snapped a three-game losing streak by beating the Washington Nationals 5-3 on Saturday. Pence was activated from the disabled list after missing 48 games with a strained right hamstring that required surgery. Welcomed by another standing ovation when he stepped into the batter's box leading off the second, Pence ripped a double off the left-field wall, and the sellout crowd jumped up to cheer once more. Anthony Rendon hit a two-run homer in the third for the Nationals, who couldn't protect an early 3-0 lead hours after acquiring All-Star closer Mark Melancon from the Pittsburgh Pirates to replace the struggling Jonathan Papelbon. Trevor Brown drew a bases-loaded walk from Blake Treinen in the seventh to give San Francisco an insurance run. Reynaldo Lopez was called up from Triple-A Syracuse to make his second major league start after losing to the Dodgers in his debut July 19. Giants: RHP Matt Cain (2-6) tries for career victory No.