Arielle Holmes’ performance in Safdie brothers’ remorseless portrait of life as a heroin addict leaves nothing outThe Safdie brothers’ divisive portrait of a New York heroin addict’s deadbeat existence hews closer to Larry Clark than Trainspotting. A cast of varyingly unwashed, toothless, abrasive semi- and non-professionals scratch harsh truths from lead Arielle Holmes’ memoir of her time on the margins.