Shares of Northern Dynasty Minerals (NYSEMKT: NAK) collapsed today after the company announced that it terminated a framework agreement with First Quantum Minerals (NASDAQOTH: FQVLF) after failing to find a path forward for developing its coveted Pebble Project in Alaska. The larger mining company has faced tremendous pressure from activists and investors alike to steer clear of developing the asset, which could risk irreparable harm to the state's coveted sockeye salmon fisheries.The move is just the latest setback for the Pebble asset, but this one ultimately could prove fatal for Northern Dynasty Minerals.