Enlarge (credit: Wikimedia) While we have a number of treatments available for clinical depression, many of them have a significant side effects, and a lot of people struggle to find a drug that they respond to. The situation is made worse by our limited understanding of the biology underlying depression. We don't know how to create targeted drugs, so most of the available treatments are blunt instruments that can take weeks to months before having an effect. In that light, it came as a bit of a shock when we discovered a drug we'd been using recreationally and for anesthesia could lift the symptoms of depression in less than 24 hours.

BING NEWS:
  • Severity of Resistant Depression Predicts Ketamine vs ECT Response
    The severity of TRD appeared to predict response to IV ketamine vs ECT. However, experts said more research is needed before drawing any definitive conclusions.
    04/24/2024 - 3:17 am | View Link
  • Ketamine bros are giving psychedelics a bad rap. That's a problem for those who need them.
    I've become unnerved by this ketamine bro culture, which threatens to halt the exciting progress in psychedelic research over the last few decades.
    04/23/2024 - 10:07 pm | View Link
  • Ketamine Produces Wide Variety of Responses in the Brain, Yale Researchers Find
    Using functional magnetic resonance imaging (fMRI), researchers found that ketamine produces a variety of different response patterns in the brains of individuals, an observation that challenges the ...
    04/22/2024 - 1:59 am | View Link
  • PharmaTher Provides Update of its Priority Original Abbreviated New Drug Application for Ketamine
    A recently published new peer-reviewed study on the real-world effectiveness of ketamine intravenous therapy demonstrated significant patient improvement for depression, anxiety and suicidal ideation.
    04/15/2024 - 9:00 pm | View Link
  • Ketamine's rapid impact on depression linked to immune system pathways
    Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.
    04/15/2024 - 12:19 pm | View Link
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