NEW YORK (AP) — Stocks that moved substantially or traded heavily Friday: Celgene Corp., down $14.63 to $121.33 The drugmaker ended late-stage testing of a potential treatment for Crohn's disease. General Electric Co., up 25 cents to $23.83 The industrial company slashed its annual forecast after a disappointing third quarter and announced plans to shed more than $20 billion in operations over the next couple of years. Skechers USA Inc., up $9.96 to $33.99 The shoe company's profit and sales were stronger than analysts expected. PayPal Holdings Inc., up $3.72 to $70.97 The payment technology company reported big gains in new users and transactions. Procter & Gamble Co., down $3.34 to $88.