Scream Queens Season 2 First Look FOX today released a new Scream Queens Season 2 first look! Season 2 will premiere on Tuesday, September 20 at 9/8c. From award-winning executive producers Ryan Murphy (“The People V. O.J. Simpson: American Crime Story,” “American Horror Story,” “Nip/Tuck”), Brad Falchuk (“American Horror Story,” “Glee,” “Nip/Tuck”) and Ian Brennan (“Glee”), Scream Queens Season 2 graduates from the college campus and into a hospital with a haunted past, as a new and terrifyingly funny mystery begins.