The hotly anticipated cosmic epic starring Matthew McConaughey as a wormhole-bound space traveler hits US theaters November 7. The new spot shows that this is, indeed, sweeping, emotionally wrought territory for Nolan, whose brainy brand of sci-fi has always been marked by a sentimental human touch—even when couched in massively scaled set pieces. Anne Hathaway, Jessica Chastain, Michael Caine, Casey Affleck, David Oyelowo, Wes Bentley, Ellen Burstyn, Topher Grace and John Lithgow costar.