Enlarge / Portrait of Beethoven by Joseph Karl Stieler, 1820. Toxocology analysis of the composer's locks of hair showed high levels of lead. (credit: Beethoven-Haus Bonn) Last year, researchers sequenced the genome of famed composer Ludwig van Beethoven for the first time, based on authenticated locks of hair. The same team has now analyzed two of the locks for toxic substances and found extremely high levels of lead, as well as arsenic and mercury, according to a recent letter published in the journal Clinical Chemistry. “It definitely shows Beethoven was exposed to high concentrations of lead,” Paul Janetto, co-author and director of the Mayo Clinic's Department of Laboratory Medicine and Pathology, told The New York Times.

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