CRISPR-Cas9, the gene-editing tool that is currently the darling of biotech and many other fields, may not be quite as miraculous as early tests suggested. A new study finds that what scientists thought of as a scalpel may be more like a felling axe, causing damage hundreds of times what was previously observed. Before anyone panics and checks out the window for mutated monstrosities, it should be said right away that this isn’t a nightmare scenario by any means: the tool can still be used in many ways safely, and the clinical repercussions of the damage are unexplored.
Crispr Dna Editing May Cause Serious Genetic Damage, Researchers Warn
Devin Coldewey, TechCrunch
Mon, 07/16/2018 - 11:56am
Topics: wtf michael kosicki kärt tomberg allan bradley wellcome sanger institute we cas9 fortunately crispr nature dna editing genetic damage cell bases repair cutting sequence indels tool job doesn handful studies previous potential thousands hundreds observed occur study thousand-pair molecule pairs base scale isn strands adjacent means unexpected
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