Ian Kinsler led off the game with a homer for Detroit, but the team with the vaunted starting pitching staff was reduced to using infielder Andrew Romine on the mound in the eighth inning. Before they opened the series against Minnesota, manager Brad Ausmus talked about the importance of the one big inning in baseball and how it usually makes the difference in who wins or loses. Escobar and Santana hit two-run homers off Ray to get the Twins out to a 6-1 lead in the second inning. The Tigers scored four times in the fifth to cut the deficit to 6-5, but Minnesota sent 14 batters to the plate in the sixth inning to break it wide open. Joe Mauer came to the plate with the bases loaded twice in the inning, driving in two with a single and forcing one home on a walk, the sixth by a Tigers pitcher in a rugged frame that also included two errors from Kinsler at second base and Nick Castellanos at third.