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Eli Manning threw two touchdown passes and linebacker Michael Boley scored on a 65-yard fumble return to lead the New York Giants to a 28-16 victory over the mistake-prone St. Louis Rams on Monday night.

Tom Brady followed up his stellar 500-yard outing in the season opener, with a 423-yard outing as the Patriots beat the Chargers 35-21 in their home opener.

Desperate to slow down Tom Brady, the Miami Dolphins tried playing 12 men on defense....

Nick Folk kicked a 50-yard field goal with 27 seconds left, giving the New York Jets a 27-24 comeback victory over the Dallas Cowboys in the final game of the NFL's first full Sunday with the commemoration of the 10-year anniversary of the 9/11 terrorist attacks as an emotional backdrop.

The Baltimore Ravens vented eight months of frustration within the span of three incredibly satisfying hours. Joe Flacco threw three touchdown passes, Haloti Ngata led an inspired defense that forced a team-record seven turnovers, and the Ravens defeated the defending AFC champion Pittsburgh Steelers 35-7 Sunday.

The Packers used a breathlessly fast tempo to build an early lead on the Saints, showcasing the precision of Aaron Rodgers’s passes and the wealth of weapons at his disposal.

Indeed, Walt Disney Co.'s ESPN -- home to "Monday Night Football" -- extended its deal through 2021 for the franchise on Thursday morning. The new deal will cost ESPN an average of $1.9 billion per season, according to a person familiar with the deal. ESPN had been paying about $1.1 billion under its current deal.

Here’s one that we considered holding until we could get confirmation. But the emails are flowing in like chocolates on a conveyor belt, and the only way to turn the machine off is to post an item on what could be a stunning development in the saga of Colts quarterback Peyton Manning.

The Colts activated Peyton Manning from the physically unable to perform list Monday, clearing the way for the four-time MVP to play early in the season....

PFT: Cincinnati finally sees rookie QB play well, and it comes during a win over the Panthers and their lauded rookie, Cam Newton.