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Alpha-1 Antitrypsin Deficiency: Causes, Symptoms & Treatment
Alpha-1 antitrypsin deficiency (sometimes just called “Alpha-1”) is an inherited genetic disorder that causes low levels of a protein (AAT) that protects your lungs. Alpha-1 increases your risk of developing certain diseases, including emphysema (damaged air sacs in your lungs), cirrhosis (liver scarring) and panniculitis (an uncommon skin ...
Alpha-1 antitrypsin deficiency: MedlinePlus Genetics
Description. Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. The signs and symptoms of the condition and the age at which they appear vary among individuals. People with alpha-1 antitrypsin deficiency usually develop the first signs and symptoms of lung disease between ages 25 and 50.
Home - Alpha-1 Foundation
The Alpha-1 Foundation is dedicated to finding a cure for Alpha-1 Antitrypsin Deficiency (Alpha-1), a progressive genetic condition that can cause damage to the lungs and/or the liver. Learn more about Alpha-1, find support, and get involved today.
Alpha-1 Antitrypsin Deficiency - Pulmonary Disorders - MSD Manual ...
Pathophysiology. Classification. Symptoms and Signs. Diagnosis. Prognosis. Treatment. Key Points. Alpha-1 antitrypsin deficiency is congenital lack of a primary lung antiprotease, alpha-1 antitrypsin, which leads to increased protease-mediated tissue destruction and emphysema in adults.
What is Alpha-1? - Alpha-1 Foundation
Alpha-1 Antitrypsin Deficiency (Alpha-1) is a genetic condition that can cause damage to the lungs and/or the liver. There is no cure for Alpha-1, but some symptoms can be managed with treatment.
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