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Bookmark or Share- BRCA gene test for breast and ovarian cancer risk - Mayo ClinicBRCA1 and BRCA2 are the most well-known genes. Testing often looks for those genes and many other genes that increase the risk of breast and ovarian cancers. Changes in these genes significantly increase the risk of many cancers, including: Breast cancer. Male breast cancer. Ovarian cancer. Prostate cancer. Pancreatic cancer.
- BRCA1 and Breast Cancer: Molecular Mechanisms and Therapeutic ...Breast cancer susceptibility gene 1 ( BRCA1) is a tumor suppressor gene, which is mainly involved in the repair of DNA damage, cell cycle regulation, maintenance of genome stability, and other important physiological processes.
- BRCA1 and BRCA2: Cancer Risks and Management (PDQ®)Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks associated with BRCA1/BRCA2, screening, risk-reduction, treatment, and prognosis.
- BRCA Gene Mutations: Cancer Risk and Genetic TestingBRCA1 and BRCA2 are sometimes called tumor suppressor genes because when they have certain changes, called harmful (or pathogenic) variants (or mutations), cancer can develop. People who inherit harmful variants in one of these genes have increased risks of several cancers—most notably breast and ovarian cancer, but also several additional ...
- BRCA1 - WikipediaBRCA1 is a human tumor suppressor gene [7] [8] (also known as a caretaker gene) and is responsible for repairing DNA. [9] BRCA1 and BRCA2 are unrelated proteins, [10] but both are normally expressed in the cells of breast and other tissue, where they help repair damaged DNA, or destroy cells if DNA cannot be repaired.
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