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Bookmark or Share- Chemical element - WikipediaA chemical element is a chemical substance that cannot be broken down into other substances by chemical reactions. The basic particle that constitutes a chemical element is the atom. Chemical elements are identified by the number of protons in the nuclei of their atoms, [1] known as the element's atomic number. [2]
- Expansive discovery of chemically diverse structured macrocyclic ... - AAASTen of the 11 chemically synthesized macrocycles displayed median inhibitory concentration (IC 50) values against HDAC6 ranging from 1.5 to 70 nM, a 10-fold to 400-fold improvement in potency compared with the minimal alkylthiol warhead present in each design (Fig. 5, A to C; fig. S20; and table S11). The most selective of these macrocycles ...
- Expansive discovery of chemically diverse structured ... - PubMedWe chemically synthesized 18 macrocycles predicted to adopt single low-energy states and determined their x-ray or nuclear magnetic resonance structures; 15 of these were very close to the design models. We illustrate the therapeutic potential of these macrocycle designs by developing selective ...
- Chemical bonding | Definition, Types, & Examples | Britannicachemical bonding, any of the interactions that account for the association of atoms into molecules, ions, crystals, and other stable species that make up the familiar substances of the everyday world. When atoms approach one another, their nuclei and electrons interact and tend to distribute themselves in space in such a way that the total ...
- CHEMICAL | definition in the Cambridge English DictionaryCHEMICAL meaning: 1. any basic substance that is used in or produced by a reaction involving changes to atoms or…. Learn more.
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