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Bookmark or Share- Tikosyn (Dofetilide): Side Effects, Uses, Dosage, Interactions ... - RxListDofetilide is metabolized to a small degree by the CYP3A4 isoenzyme of the cytochrome P450 system and an inhibitor of this system could increase systemic dofetilide exposure. More important, dofetilide is eliminated by cationic renal secretion, and three inhibitors of this process have been shown to increase systemic dofetilide exposure.
- Clinical use of dofetilide - UpToDateDofetilide is a class III antiarrhythmic agent ( table 1) available for the acute termination of atrial fibrillation or flutter, as well as prevention of atrial fibrillation or flutter recurrence. Dofetilide has also been used in an off-label manner to treat paroxysmal supraventricular tachycardias. Some investigators have studied the efficacy ...
- Dofetilide Uses, Side Effects & Warnings - Drugs.comDofetilide is a heart rhythm medicine, also called an antiarrhythmic. Dofetilide is used to help keep the heart beating normally in people with certain heart rhythm disorders of the atrium (the upper chambers of the heart that allow blood to flow into the heart). Dofetilide is used in people with atrial fibrillation or atrial flutter.
- Tikosyn Capsules - Uses, Dosage, Side Effects, Warnings - Drugs.comTikosyn (dofetilide) is an antiarrhythmic drug that is used to treat an abnormal heartbeat. Antiarrhythmic drugs are classified using a system known as the Vaughan Williams Classification System and under this system Tikosyn is classed as a Class III antiarrhythmic, which is a group of drugs that act as potassium channel blockers. ...
- Dofetilide: Uses & Side Effects - Cleveland ClinicWhat is the drug dofetilide used for? Dofetilide uses include treating and preventing: Atrial fibrillation (Afib, an irregular heart rhythm that starts in your heart’s upper chambers).; Atrial flutter (another abnormal heart rhythm that begins in the upper chambers of your heart).; Healthcare providers also prescribe dofetilide for “off-label” uses.
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