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A Brief History of Human Challenge Trials - Smithsonian Magazine
Human challenge trials are as old as inoculation itself. In 1796, English surgeon Edward Jenner tested the world’s first vaccine by exposing his gardener’s 8-year-old son to cowpox and then ...
Why Human Subjects Research Protection Is Important - PMC
Methods: This paper reviews the history of human subjects participating in research, including examples of egregious events, and the ethical analyses that precipitated the evolution of the mandated protections afforded participants in research under current federal regulations.
Human subject research - Wikipedia
Human subject research is systematic, scientific investigation that can be either interventional (a "trial") or observational (no "test article") and involves human beings as research subjects, commonly known as test subjects.
Human Experimentation: An Introduction to the Ethical Issues
The Ethical Landscape. Ethical issues in human research generally arise in relation to population groups that are vulnerable to abuse. For example, much of the ethically dubious research conducted in poor countries would not occur were the level of medical care not so limited. Similarly, the cruelty of the Tuskegee experiments clearly reflected ...
Clinical trials - World Health Organization (WHO)
WHO Response. Clinical trials are a type of research that studies new tests and treatments and evaluates their effects on human health outcomes. People volunteer to take part in clinical trials to test medical interventions including drugs, cells and other biological products, surgical procedures, radiological procedures, devices, behavioural ...
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