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Bookmark or Share- Interleukin 13 and its role in gut defence and inflammation | GutThis review will focus on the IL-13 cytokine and receptor pathways, the role of IL-13 in gut mucosal immune responses and inflammatory diseases, and highlight development and testing of drugs targeting IL-13 and the IL-13 receptor system.
- Interleukin-13 as an important cytokine: A review on its roles ... - PubMedInterleukin-13 (IL-13) as a pleiotropic cytokine acts through the IL-13Ra1/IL-4Ra complex to induce activation responses which contribute to the inflammatory diseases. Genetic polymorphisms in IL-13 and its receptor components have been proved to be associated with higher disease prevalence rates.
- Interleukin 13 - WikipediaInterleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located on chromosome 5q31.1 with a length of 1.4kb. It has a mass of 13 kDa and folds into 4 alpha helical bundles.
- Interleukin-13 - DocCheck FlexikonInterleukin-13 wird durch das Gen IL13 kodiert, das sich mit einer Länge von ca. 1.400 Basenpaaren auf Chromosom 5 in Position 5q31 befindet. Funktion IL-13 ist als Botenstoff an Prozessen des Immunsystems beteiligt, insbesondere an der Auslösung allergischer Reaktionen.
- IL-13 Effector Functions* | Annual ReviewsThe mechanisms that regulate IL-13 production and/or function have also been investigated, and IL-4, IL-12, IL-18, IFN-γ, IL-10, TGF-β, TNF-α, and the IL-4/IL-13 receptor complex play important roles. This review highlights the effector functions of IL-13 and describes multiple pathways for modulating its activity in vivo.
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