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- Multicentric carpotarsal osteolysis syndrome - Genetic and Rare ...Multicentric carpotarsal osteolysis syndrome is a very rare condition characterized by progressive loss of some of the bones of the hand and feet, usually the carpal (bones of the wrist) and tarsal bones (bones of the ankle), as well as chronic kidney (renal) failure in many cases. The bone problems lead to deformity and disability.
- Multidisciplinary Team and Research Advancing Care for MCTO | Children ...After diagnosing a young girl with multicentric carpotarsal osteolysis (MCTO), doctors led a multidisciplinary effort to slow the disease's progression.
- Multicentric Carpo-Tarsal Osteolysis Syndrome (MCTO) and “Function ...Multicentric Carpo-Tarsal Osteolysis Syndrome (MCTO) is an autosomal dominant disease with increased bone reabsorption in the carpus and tarsus and the elbows, knees and spine. The disease is extremely heterogeneous and secondary and tertiary injuries vary widely and can lead to progressive disability and severe functional limitations.
- About MCTO — Sophie's NeighborhoodMulticentric Carpotarsal Osteolysis (MCTO) is a rare skeletal dysplasia characterized by aggressive osteolysis [resorption of bone], particularly affecting the carpal and tarsal bones, and is frequently associated with renal failure.
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