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Bookmark or Share- NYC Council Announces New Law is in Effect to Support Small Businesses ...The law, sponsored by Council Member Julie Menin, was passed by the New York City Council in November 2023 and signed into law later that month. The reforms under Local Law 151 include provisions intended to reduce financial and other burdens on small businesses, such as simplifying signage and ...
- Therapeutic implications of menin inhibition in acute leukemiasMenin was first described after discovery of germline mutations in the gene responsible for the multiple endocrine neoplasia type 1 syndrome and was named MEN1.A The gene is located on chromosome ...
- Menin “reads” H3K79me2 mark in a nucleosomal context | Science - AAASA reader for H3K79me2. Decoding a histone modification requires identification of proteins that “read” the mark. Methylation of histone H3 lysine-79 (H3K79) plays key roles in gene regulation, but it remains a mystery how this histone mark is recognized and interpreted by specific readers. Lin et al. identified the protein menin as a bona ...
- MEN1 mutations mediate clinical resistance to menin inhibitionMenin is a chromatin adaptor protein that is critical for the formation and stability of highly conserved multiprotein complexes on chromatin, including MLL1 (also known as KMT2A) and MLL2 (also ...
- Unlocking the Fountain of Youth: Dietary Supplement Reverses Aging by ...Summary: Supplementing the amino acid D-serine helped to mitigate some of the age-related changes associated with a decline of the hypothalamic hormone Menin in mouse models. Source: PLOS Decline in the hypothalamic Menin may play a key role in aging, according to a new study in PLOS Biology by Lige Leng of Xiamen University, Xiamen, China, and colleagues.
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