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Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis ...
Patisiran, an RNA interference therapeutic agent with a lipid nanoparticle delivery system, targets the common 3′ untranslated region of TTR messenger RNA in the liver to reduce circulating...
Patisiran: First Global Approval - PubMed
Patisiran has been developed by Alnylam Pharmaceuticals; it was recently approved in the USA for the treatment of the polyneuropathy of hereditary TTR-mediated amyloidosis (hATTR) in adults and subsequently approved in the EU for the treatment of hATTR in adults with stage 1 or 2 polyneuropathy.
Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin ...
Patisiran, an investigational RNA interference therapeutic agent, specifically inhibits hepatic synthesis of transthyretin. In this phase 3 trial, we randomly assigned patients with hereditary...
Patisiran Uses, Side Effects & Warnings - Drugs.com
Patisiran is used to treat adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (damage of multiple nerves throughout the body). Patisiran may also be used for purposes not listed in this medication guide. Patisiran side effects.
Patisiran - StatPearls - NCBI Bookshelf
Patisiran, a liposomal siRNA molecule, is used to treat patients with polyneuropathy (sensorimotor and autonomic neuropathy) and cardiomyopathy associated with hereditary transthyretin-mediated amyloidosis and wild-type transthyretin-mediated amyloidosis (ATTRwt).
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