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Bookmark or Share- Approaches to the release of a master cell bank of PER.C6 ...PMID: 16566444. Abstract. At Merck and Co. we have developed a recombinant E1 deficient adenovirus type 5 vaccine vector for HIV-1 and have adopted the PER.C6 cell line as a cell substrate for the manufacture of this vector for Phase I and II clinical trials.
- How cells taken from decades-old fetal tissue are used in ...Johnson & Johnson used a different cell line called PER.C6, also derived from fetal cells, to test its vaccine’s effectiveness against Covid-19. Kreigstein said that in his experience most...
- Here are the facts about fetal cell lines and COVID-19 vaccinesThe PER.C6 cell line, for instance, is derived from immortalized retinal cells from an 18-week-old fetus aborted in 1985. Johnson & Johnson uses PER.C6 to produce its COVID-19 vaccine.
- Crucell: Biopharmaceuticals-As Human as They Get - Cell PressPER.C6 cells are immortalized primary human embryonic retinal cells engineered to express Ad 5 E1A and E1B. The development of matched Ad vectors with no sequence overlap eliminates the RCA problem when packaged in these cells. However, there are many more reasons for the over 25 licensees of Crucell's PER.C6 technology to value these cells.
- PER.C6(®) cells as a serum-free suspension cell platform for ...PER.C6 (®) cells as a serum-free suspension cell platform for the production of high titer poliovirus: a potential low cost of goods option for world supply of inactivated poliovirus vaccine. Vaccine. 2013 Jan 21;31 (5):850-6. doi: 10.1016/j.vaccine.2012.10.070. Epub 2012 Oct 30.
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