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Intestinal Peyer’s Patches: Structure, Function, and
The organized GALT is composed of follicles including Peyer's patches (PPs) in the small intestine, colonic patches, and isolated lymphoid follicles, which induce immune reactions. On the other hand, diffuse GALT is dominated by lymphoid cells diffusely distributed in lamina propria.
Class-switch recombination to IgA in the Peyer’s patches requires ...
The most important inductive sites for gut IgA B-cell responses are the Peyer’s patches (PP) of the small intestine. 1,2,3 Although significant efforts have been devoted to understanding how ...
Peyer Patches - StatPearls - NCBI Bookshelf
Peyer's patches are also culprits in the development of idiopathic intussusception. Intussusception most commonly occurs in infants, especially during the weaning period & also due to viral infection like adenovirus in early childhood. This presentation suggests that the exposure of the infant's gut to new pathogens causes the hypertrophy of ...
Mast cells help organize the Peyer’s patch niche for ... - Science
Peyer’s patches (PPs) are lymphoid structures situated adjacent to the intestinal epithelium that support B cell responses that give rise to many intestinal IgA-secreting cells. Induction of isotype switching to IgA in PPs requires interactions between B cells and TGFβ-activating conventional dendritic cells type 2 (cDC2s) in the ...
Human gut-associated lymphoid tissues (GALT); diversity ... - Nature
Gut-associated lymphoid tissues (GALT) are the key antigen sampling and adaptive immune inductive sites within the intestinal wall. Human GALT includes the multi-follicular Peyer’s patches of ...
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