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Bookmark or Share- RB1 Gene - GeneCards | RB Protein | RB AntibodyRB1 (RB Transcriptional Corepressor 1) is a Protein Coding gene. Diseases associated with RB1 include Retinoblastoma and Small Cell Cancer Of The Lung. Among its related pathways are Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) and Regulation of activated PAK-2p34 by proteasome mediated degradation.
- The retinoblastoma tumor-suppressor gene, the exception that ... - NatureThe retinoblastoma tumor-suppressor gene ( Rb1) is centrally important in cancer research. Mutational inactivation of Rb1 causes the pediatric cancer retinoblastoma, while deregulation of...
- The Cars - Red Bull RacingNumber of cylinders 10. Number of valves 4 per cylinder. Oil Castrol. Capacity 3,000cc. Vee angle 90-degrees. Weight N/A. Max RPM 19,000RPM. Power output 915HP.
- Retinoblastoma protein - WikipediaThe retinoblastoma protein (protein name abbreviated Rb; gene name abbreviated Rb, RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers. [5] . One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide.
- Cell cycle and beyond: Exploiting new RB1 controlled mechanisms for ...Canonically, RB1 regulates cell cycle progression and represents the down-stream target for CDK4/6 inhibitors that are in clinical use. However, newly discovered features of the RB1-pathway suggest new therapeutic strategies to counter resistance and improve precision medicine.
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