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Bookmark or Share- Retrovirus | Definition, Examples, Diseases, Replication, & Factsretrovirus, any of a group of viruses that belong to the family Retroviridae and that characteristically carry their genetic blueprint in the form of ribonucleic acid ( RNA ). Retroviruses are named for an enzyme known as reverse transcriptase, which was discovered independently in 1971 by American virologists Howard Temin and David Baltimore.
- Overview of Retrovirology - PMC - National Center for Biotechnology ...The discovery of retroviral oncogenes established the central paradigm that altered cellular genes can provide a dominant signal initiating cancer development. Their unique replication mechanism and their integration into cellular DNA allow these viruses to alter the properties of their hosts beyond the life span of the infected individual and ...
- Physical principles of retroviral integration in the human genome - NatureIntroduction. Retroviruses are pathogens that infect organisms by inserting their DNA within the genome of the host. Once integrated, they exploit the transcription machinery already in place to...
- Retrovirus - National Human Genome Research InstituteDefinition. A retrovirus is a virus that uses RNA as its genomic material. Upon infection with a retrovirus, a cell converts the retroviral RNA into DNA, which in turn is inserted into the DNA of the host cell. The cell then produces more retroviruses, which infect other cells.
- Retrovirus - WikipediaThe retroviral envelope serves three distinct functions: protection from the extracellular environment via the lipid bilayer, enabling the retrovirus to enter/exit host cells through endosomal membrane trafficking, and the ability to directly enter cells by fusing with their membranes.
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