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Bookmark or Share- Yi Zhang, PhD | Investigator Profile | 2005-Present - HHMIYi Zhang seeks to understand how epigenetic-mediated changes in chromatin structure affect gene expression, which in turn regulates mammalian development and disease. Working in cultured cells and mice, Zhang and his team have applied biochemical and functional approaches to identify and characterize numerous chromatin-modifying enzymes over ...
- Yi Zhang - Google Scholar2013. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. S Ito, L Shen, Q Dai, SC Wu, LB Collins, JA Swenberg, C He, Y Zhang. Science 333 (6047), 1300-1303. , 2011. 3808. 2011. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
- Yi Zhang, Ph.D. | Harvard Stem Cell Institute (HSCI)Yi Zhang serves as the Fred S. Rosen endowed Professor of Pediatrics and Professor of Genetics at Harvard Medical School, and is an Investigator of the Howard Hughes Medical Institute. Zhang received his B.S. from China Agriculture University in 1984, and his Ph.D. from Florida State University in 1995.
- the PI — the Zhang LabDr. Yi Zhang. Yi Zhang is currently an Investigator of the Howard Hughes Medical Institute, and the Fred Rosen Chair Professor of Genetics at Harvard Medical School and Boston Children’s Hospital. He obtained his Ph.D. from the Institute of Molecular Biophysics at Florida State University, where he studied the "hammerhead" ribozyme.
- Yi Zhang | Harvard Biological & Biomedical Sciences PhD ProgramYi Zhang. Fred S. Rosen Professor of Pediatrics, Professor of Genetics. The Zhang lab is interested in how epigenetic modification-mediated dynamic changes in chromatin structure affects gene expression, stem cell reprogramming, germ cell development, beta-cell generation, and drug addiction.
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