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Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
Nature - This study shows that ZMapp, an optimized cocktail of three monoclonal antibodies that has been pressed into clinical use in response to the current Ebola virus disease epidemic, was...
A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection
body cocktail ZMapp is a promising immune-based treatment for Ebola virus disease (EVD). METHODS Beginning in March 2015, we conducted a randomized, controlled trial of ZMapp
Study finds Ebola treatment ZMapp holds promise, although results not ...
ZMapp, developed by Mapp Biopharmaceutical, Inc., based in San Diego, is composed of three different laboratory-made proteins called monoclonal antibodies. The treatment is designed to prevent the progression of EVD within the body by targeting the main surface protein of the Ebola virus.
New antibodies best ZMapp in Ebola trial | Nature Biotechnology
ZMapp, the only candidate drug previously studied in Ebola patients, was being used as the control arm in PALM because it showed a favorable survival trend in an earlier trial.
A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection
Data from studies in nonhuman primates suggest that the triple monoclonal antibody cocktail ZMapp is a promising immune-based treatment for Ebola virus disease (EVD). Beginning in March 2015, we...
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