Roche Holding AG is close to a deal to buy Philadelphia-based Spark Therapeutics for nearly $5 billion, the Wall Street Journal is reporting. Citing sources familiar with the deal, the Journal reports that it could be announced "on Monday if not sooner." If the deal goes through, Roche would be paying a huge premium for the gene therapy company Spark, whose market value was about $2 billion when the markets closed on Friday. The Journal reported that another company was involved in the bidding…

 

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