FORT MCMURRAY, Alberta — A raging wildfire emptied Canada’s main oil sands city, destroying entire neighborhoods of Fort McMurray, Alberta, where officials warned Wednesday that all efforts to suppress the fire have failed. About 88,000 residents successfully evacuated as flames moved into the city surrounded by wilderness in the heart of Canada’s oil sands. Unseasonably hot temperatures combined with dry conditions have transformed the boreal forest in much of Alberta into a tinder box. Officials estimated the fire at 18,500 acres and said they expect it to be worse Wednesday as strong winds and high temperatures “will again create explosive conditions.” Federal Public Safety Minister Ralph Goodale called it one of the largest fire evacuations in Canadian history, if not the largest. Canadian Prime Minister Justin Trudeau said while the full extent of the damage isn’t yet known he called it “absolutely devastating” and said there’s a loss on a scale that’s hard to imagine. Trudeau noted climate change is contributing to an increase in extreme weather and fires but said it’s difficult to establish a direct link.