At 0-3, the 49ers could travel America in search of their first win. Their odyssey will begin Sunday in the Southwest (at Arizona) before they move to the Midwest (at Indianapolis on Oct. 8) and finish on the East Coast (at Washington on Oct. 15). Their nearly 10,000-miles-in-16-days journey will mark the first time they’ve played three straight regular-season road games since 2005.