TOKYO (AP) — Shares were mixed Wednesday, as weak data from China sapped the upward momentum from an overnight rally on a flurry of deals in the pharmaceutical sector. A preliminary survey of Chinese manufacturers by HSBC showed slight improvements in prices and demand, but contractions in new export orders and employment in April. [...] Japan's Nikkei 225 index gained 1.1 percent to 14,546.27 as export manufacturers' shares advanced on the relative weakness of the yen.