Negotiating a nuclear deal with Iran in 2015 was hard; renegotiating more or less the same nuclear deal with Iran after the U.S. withdrawal is harder than you’d think. And that’s before you factor in an Israeli prime minister who has little left to lose. Here’s what happens next with Iranian nuclear negotiations, 2021 edition. Why It Matters: On April 11, a bombing at Iran’s Natanz nuclear facility, the country’s biggest enrichment site, took out the power supply and reportedly destroyed thousands of centrifuges.