It has been tough for breweries in central Denver over the past year as at least half a dozen have closed, including Mockery, MobCraft, Wah Gwaan, Dos Luces, Counter Culture and Lowdown. Alpine Dog Brewing, at 1308 E. 17th Ave., will join that list when it shuts its doors on March 31. “After nearly 10 years of great beer, great friends and the most fun and epic of times, Alpine Dog will be selling or otherwise closing the brewery,” the business wrote on social media.