After more than 50 years as a Schedule I substance, marijuana is slated to get reclassified. In a historic shift, the Drug Enforcement Administration reportedly plans to modify the drug’s designation under the Controlled Substances Act from a category that includes drugs like heroin and meth to the less dangerous but still illegal Schedule III, alongside ketamine and anabolic steroids. Schedule I drugs, as my colleague Julia Métraux reported last week, by definition have a “high potential” for abuse without any “currently accepted medical use.” With the change to Schedule III, explains Harvard neuroscientist Staci Gruber, who studies the effect of marijuana on our brains, “We’re no longer saying ‘no accepted medical value.’ That’s a big difference.