The Prison Break Comic-Con trailer Wentworth Miller, Dominic Purcell, Sarah Wayne Callies, Robert Knepper, and producers Vaun Wilmott and Michael Horowitz were present for the Prison Break Comic-Con panel in San Diego, where they revealed this new trailer and clip! Prison Break is back and ready for its biggest escape yet. In the thrilling new 2017 event series Prison Break, original series stars Wentworth Miller, Dominic Purcell, Sarah Wayne Callies, Amaury Nolasco, Robert Knepper, Rockmond Dunbar and Paul Adelstein are reunited for an all-new adventure spanning the globe and featuring the signature thrills and cliffhangers that were hallmarks of the original series when it aired on FOX from 2005-2009. The original action drama centered on Michael Scofield (Miller), a young man determined to save his convicted brother, Lincoln Burrows (Purcell), from death row by hatching an elaborate plan to escape from prison.